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inherited. This is explained by the fact that each gene set is present, not
                                     as a single long thread of DNA, but as separate independent pieces,
                                     each called a chromosome. Thus, each cell will have two copies of each
                                     chromosome, one each from the male and female parents. Every germ-
                                     cell will take one chromosome from each pair and these may be of either
                                     maternal or paternal origin. When two germ cells combine, they will
                                     restore the normal number of chromosomes in the progeny, ensuring
                                     the stability of the DNA of the species. Such a mechanism of inheritance
                                     explains the results of the Mendel experiments, and is used by all
                                     sexually reproducing organisms. But asexually reproducing organisms
                                     also follow similar rules of inheritance. Can we work out how their
                                     inheritance might work?


                                     8.2.4 Sex Determination

                                     We have discussed the idea that the two sexes participating in sexual
                                     reproduction must be somewhat different from each other for a number
                                                   of reasons. How is the sex of a newborn individual
                                                   determined? Different species use very different strategies
                                                   for this. Some rely entirely on environmental cues. Thus,
                                                   in some animals like a few reptiles, the temperature at
                                                   which fertilised eggs are kept determines whether the
                                                   animals developing in the eggs will be male or female. In
                                                   other animals, such as snails, individuals can change sex,
                                                   indicating that sex is not genetically determined. However,
                                                   in human beings, the sex of the individual is largely
                                                   genetically determined. In other words, the genes inherited
                                                   from our parents decide whether we will be boys or girls.
                                                   But so far, we have assumed that similar gene sets are
                                                   inherited from both parents. If that is the case, how can
                                                   genetic inheritance determine sex?
                                                       The explanation lies in the fact that all human
                                                   chromosomes are not paired. Most human chromosomes
                                                   have a maternal and a paternal copy, and we have 22
                                                   such pairs. But one pair, called the sex chromosomes, is
                                                   odd in not always being a perfect pair. Women have a
                                                   perfect pair of sex chromosomes, both called X. But men
                                                   have a mismatched pair in which one is a normal-sized X
                                                   while the other is a short one called Y. So women are XX,
                                                   while men are XY. Now, can we work out what the
                                                   inheritance pattern of X and Y will be?
                                                       As Fig. 8.6 shows, half the children will be boys and
                                                   half will be girls. All children will inherit an X chromosome
                                                   from their mother regardless of whether they are boys or
                                                   girls. Thus, the sex of the children will be determined by
                                                   what they inherit from their father. A child who inherits
              Figure  8.6
              Figure 8.6
              Figure 8.68.6
              Figure 8.6
              Figure
              Sex determination in                 an X chromosome from her father will be a girl, and one
              human beings                         who inherits a Y chromosome from him will be a boy.
               132                                                                                   Science


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